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Probiotics: Are Bugs a Man's Best Friend?


Medically Reviewed On: May 15, 2003

By Erica Heilman

Introduced in the seventies as an effective way to plump up livestock, probiotics may soon be playing an important role in disease prevention and treatment—this time in humans. These tiny organisms are capable of protecting areas of the body from the negative effects of bacterial imbalance. But unlike antibiotics, which kill harmful microbes in the body, probiotics simply take up residence in the body and neutralize the effects of offending bacteria.

Though they have only come under serious investigation by the medical community in recent years, these natural bacteria have been a popular folk remedy for intestinal afflictions for thousands of years, and can be found in various forms at most health food stores. Dairy foods, particularly yogurt that contain live bacterial cultures, have long been used to prevent or treat common intestinal problems.

The exact mechanism by which probiotics work in the gastrointestinal tract is still not entirely understood, but their benefits are widely-touted. There is anecdotal evidence that people with common disorders such as diarrhea, inflammatory bowel disease, and irritable bowel syndrome benefit from taking products containing probiotics, and there are studies currently underway to determine just how, and why they work.

Below, Professor of Medicine Dr. Claudio Fiocchi, of Case Western Reserve University in Cleveland, Ohio, talks about these beneficial bacteria, and what role they might one day play in the prevention and treatment of gastrointestinal disorders.

What role do bacteria normally play in the gastrointestinal tract?
The bacteria that we have in the gastrointestinal tract are essential, and without them, we can't live. In very simple terms, they break down the food, and allow us to absorb nutrients that are beneficial to us. Many vitamins, for instance, or essential amino acids, can only be absorbed by the body after a bacteria has broken them down. So they're absolutely essential in that respect.

How do probiotics function in the body?
Most of the information about how they work is not particularly solid from a scientific standpoint. But when probiotics are introduced into the body, they establish a rapport with other bacteria that naturally reside in the body. The probiotics live together with the preexisting bacteria in our bodies, and counteract the negative effects of other bacteria. But probiotics only persist as long as they are continually ingested. So if you don't eat any foods or supplements containing probiotics, after about a month, they will be all gone.

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